The chromogranin A-derived antifungal peptide CGA-N9 induces apoptosis in Candida tropicalis

CGA-N9, a peptide derived from human chromogranin A (CGA), was found to have antimicrobial activity in our previous investigation, but its mechanism of action remains unclear. Herein, the mechanism of action of CGA-N9 was investigated. We found that CGA-N9 induced the depolarization of the cell memb...

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Veröffentlicht in:Biochem J
Hauptverfasser: Li, Ruifang, Chen, Chen, Zhang, Beibei, Jing, Hongjuan, Wang, Zichao, Wu, Chunling, Hao, Pu, Kuang, Yong, Yang, Minghang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824672/
https://ncbi.nlm.nih.gov/pubmed/31652303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190483
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