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Novel COX-2 products of n-3 polyunsaturated fatty acid-ethanolamine-conjugates identified in RAW264.7 macrophages

Cyclooxygenase 2 (COX-2) plays a key role in the regulation of inflammation by catalyzing the oxygenation of PUFAs to prostaglandins (PGs) and hydroperoxides. Next to this, COX-2 can metabolize neutral lipids, including endocannabinoid-like esters and amides. We developed an LC-HRMS-based human reco...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: de Bus, Ian, Zuilhof, Han, Witkamp, Renger, Balvers, Michiel, Albada, Bauke
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824491/
https://ncbi.nlm.nih.gov/pubmed/31455615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M094235
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