N-acetyl-seryl-aspartyl-lysyl-proline treatment protects heart against excessive myocardial injury and heart failure in mice

Myocardial infarction (MI) in mice results in cardiac rupture at 4–7 days after MI, whereas cardiac fibrosis and dysfunction occur later. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) has anti-inflammatory, anti-fibrotic, and pro-angiogenic properties. We hypothesized that Ac-SDKP reduces cardiac...

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Detalhes bibliográficos
Publicado no:Can J Physiol Pharmacol
Main Authors: Peng, Hongmei, Xu, Jiang, Yang, Xiao-Ping, Kassem, Kamal M., Rhaleb, Imane A., Peterson, Ed, Rhaleb, Nour-Eddine
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824427/
https://ncbi.nlm.nih.gov/pubmed/30998852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2019-0047
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