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Effect of Caffeine on the Bioavailability and Pharmacokinetics of an Acetylsalicylic Acid-Paracetamol Combination: Results of a Phase I Study

INTRODUCTION: Caffeine is used as an adjuvant in analgesic combinations to enhance their efficacy. The present study aimed to determine the effect of caffeine on the pharmacokinetics of acetylsalicylic acid (ASA) and paracetamol when used as a fixed-dose ASA/paracetamol/caffeine combination. METHODS...

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Detalhes bibliográficos
Publicado no:Adv Ther
Main Authors: Weiser, Thomas, Weigmann, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824350/
https://ncbi.nlm.nih.gov/pubmed/30758744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-019-0891-5
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