Liver Glycogen Phosphorylase Deficiency Leads to Profibrogenic Phenotype in a Murine Model of Glycogen Storage Disease Type VI

Mutations in the liver glycogen phosphorylase (Pygl) gene are associated with the diagnosis of glycogen storage disease type VI (GSD‐VI). To understand the pathogenesis of GSD‐VI, we generated a mouse model with Pygl deficiency (Pygl (−/−)). Pygl (−/−) mice exhibit hepatomegaly, excessive hepatic gl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hepatol Commun
Egile Nagusiak: Wilson, Lane H., Cho, Jun‐Ho, Estrella, Ana, Smyth, Joan A., Wu, Rong, Chengsupanimit, Tayoot, Brown, Laurie M., Weinstein, David A., Lee, Young Mok
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824077/
https://ncbi.nlm.nih.gov/pubmed/31701076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1426
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