Systemic high-dose intravenous methotrexate in patients with central nervous system metastatic breast cancer

BACKGROUND: Infusion of high-dose intravenous methotrexate (MTX) has been demonstrating to penetrate the blood-brain barrier. The aim of this present study was to assess the efficacy and safety of high dose MTX in patients with central nervous system (CNS) metastases of breast cancer. METHODS: Twent...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Bazan, F., Dobi, E., Royer, B., Curtit, E., Mansi, L., Menneveau, N., Paillard, M. J., Meynard, G., Villanueva, C., Pivot, X., Chaigneau, L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823971/
https://ncbi.nlm.nih.gov/pubmed/31675937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6228-6
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