Coagulation FXIII-A Protein Expression Defines Three Novel Sub-populations in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia Characterized by Distinct Gene Expression Signatures

Background: Leukemic B-cell precursor (BCP) lymphoblasts were identified as a novel expression site for coagulation factor XIII subunit A (FXIII-A). Flow cytometry (FC) revealed three distinct expression patterns, i.e., FXIII-A negative, FXIII-A dim, and FXIII-A bright subgroups. The FXIII-A negativ...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Gyurina, Katalin, Kárai, Bettina, Ujfalusi, Anikó, Hevessy, Zsuzsanna, Barna, Gábor, Jáksó, Pál, Pálfi-Mészáros, Gyöngyi, Póliska, Szilárd, Scholtz, Beáta, Kappelmayer, János, Zahuczky, Gábor, Kiss, Csongor
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Oncology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823876/
https://ncbi.nlm.nih.gov/pubmed/31709175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01063
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