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“Close-to-Release”: Spontaneous Bioorthogonal Uncaging Resulting from Ring-Closing Metathesis

[Image: see text] Bioorthogonal uncaging reactions offer versatile tools in chemical biology. In recent years, reactions have been developed to proceed efficiently under physiological conditions. We present herein an uncaging reaction that results from ring-closing metathesis (RCM). A caged molecule...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Sabatino, Valerio, Rebelein, Johannes G., Ward, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823642/
https://ncbi.nlm.nih.gov/pubmed/31503474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b07193
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