Dendritic Cell-Based Immunotherapy in Advanced Sarcoma and Neuroblastoma Pediatric Patients: Anti-cancer Treatment Preceding Monocyte Harvest Impairs the Immunostimulatory and Antigen-Presenting Behavior of DCs and Manufacturing Process Outcome

Despite efforts to develop novel treatment strategies, refractory and relapsing sarcoma, and high-risk neuroblastoma continue to have poor prognoses and limited overall survival. Monocyte-derived dendritic cell (DC)-based anti-cancer immunotherapy represents a promising treatment modality in these n...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Hlavackova, Eva, Pilatova, Katerina, Cerna, Dasa, Selingerova, Iveta, Mudry, Peter, Mazanek, Pavel, Fedorova, Lenka, Merhautova, Jana, Jureckova, Lucie, Semerad, Lukas, Pacasova, Rita, Flajsarova, Lucie, Souckova, Lenka, Demlova, Regina, Sterba, Jaroslav, Valik, Dalibor, Zdrazilova-Dubska, Lenka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823179/
https://ncbi.nlm.nih.gov/pubmed/31709173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01034
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