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Rapamycin attenuates liver injury caused by vinyl chloride metabolite chloroethanol and lipopolysaccharide in mice.

Vinyl chloride (VC) is a prevalent environmental toxicant that is rapidly metabolized within the liver. Its metabolites have been shown to directly cause hepatic injury at high exposure levels. We have previously reported that VC metabolite, chloroethanol (CE), potentiates liver injury caused by lip...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Lang, Anna L., Krueger, Austin M., Schnegelberger, Regina D, Kaelin, Brenna R., Rakutt, Maxwell J., Chen, Liya, Arteel, Gavin E, Beier, Juliane I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823165/
https://ncbi.nlm.nih.gov/pubmed/31499194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2019.114745
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