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Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies

The use of viruses infecting bacteria (bacteriophages or phages) to treat bacterial infections has been ongoing clinically for approximately 100 years. Despite that long history, the growing international crisis of resistance to standard antibiotics, abundant anecdotal evidence of efficacy, and one...

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Bibliographic Details
Published in:Microbiol Mol Biol Rev
Main Authors: Dąbrowska, Krystyna, Abedon, Stephen T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822990/
https://ncbi.nlm.nih.gov/pubmed/31666296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00012-19
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