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Quantitative Glycomic Analysis by Mass-Defect-Based Dimethyl Pyrimidinyl Ornithine (DiPyrO) Tags and High-Resolution Mass Spectrometry

We recently developed a novel amine-reactive mass-defect-based chemical tag, dimethyl pyrimidinyl ornithine (DiPyrO), for quantitative proteomic analysis at the MS(1) level. In this work, we further extend the application of the DiPyrO tag, which provides amine group reactivity, optical detection ca...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Chen, Bingming, Feng, Yu, Frost, Dustin C., Zhong, Xuefei, Buchberger, Amanda Rae, Johnson, Jillian, Xu, Meng, Kim, Miriam, Puccetti, Diane, Diamond, Carol, Ikonomidou, Chrysanthy, Li, Lingjun
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822904/
https://ncbi.nlm.nih.gov/pubmed/29779369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b00548
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