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Variance prior specification for a basket trial design using Bayesian hierarchical modeling

BACKGROUND: In the era of targeted therapies, clinical trials in oncology are rapidly evolving, wherein patients from multiple diseases are now enrolled and treated according to their genomic mutation(s). In such trials, known as basket trials, the different disease cohorts form the different basket...

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Publicado en:Clin Trials
Main Authors: Cunanan, Kristen M., Iasonos, Alexia, Shen, Ronglai, Gönen, Mithat
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822679/
https://ncbi.nlm.nih.gov/pubmed/30526008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774518812779
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