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Variance prior specification for a basket trial design using Bayesian hierarchical modeling

BACKGROUND: In the era of targeted therapies, clinical trials in oncology are rapidly evolving, wherein patients from multiple diseases are now enrolled and treated according to their genomic mutation(s). In such trials, known as basket trials, the different disease cohorts form the different basket...

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Bibliografske podrobnosti
izdano v:Clin Trials
Main Authors: Cunanan, Kristen M., Iasonos, Alexia, Shen, Ronglai, Gönen, Mithat
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822679/
https://ncbi.nlm.nih.gov/pubmed/30526008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774518812779
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