Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial

IMPORTANCE: Excessive bleeding is a common complication of cardiac surgery. An important cause of bleeding is acquired hypofibrinogenemia (fibrinogen level <1.5-2.0 g/L), for which guidelines recommend fibrinogen replacement with cryoprecipitate or fibrinogen concentrate. The 2 products have impo...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Callum, Jeannie, Farkouh, Michael E., Scales, Damon C., Heddle, Nancy M., Crowther, Mark, Rao, Vivek, Hucke, Hans-Peter, Carroll, Jo, Grewal, Deep, Brar, Sukhpal, Bussières, Jean, Grocott, Hilary, Harle, Christopher, Pavenski, Katerina, Rochon, Antoine, Saha, Tarit, Shepherd, Lois, Syed, Summer, Tran, Diem, Wong, Daniel, Zeller, Michelle, Karkouti, Keyvan
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822637/
https://ncbi.nlm.nih.gov/pubmed/31634905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.17312
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