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Toll-like receptor 7 contributes to inflammation, organ injury, and mortality in murine sepsis

BACKGROUND: Sepsis remains a critical illness with high mortality. The authors have recently reported that mouse plasma RNA concentrations are markedly increased during sepsis and closely associated with its severity. Toll-like receptor 7, originally identified as the sensor for single-stranded RNA...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Jian, Wenling, Gu, Lili, Williams, Brittney, Feng, Yan, Chao, Wei, Zou, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822621/
https://ncbi.nlm.nih.gov/pubmed/31045897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000002706
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