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Neuromedin B mediates IL-6 and COX-2 expression through NF-κB/P65 and AP-1/C-JUN activation in human primary myometrial cells

Neuromedin B (NMB) and its receptor regulate labor onset by mediating inflammatory factors; however the underlying mechanisms remain poorly understood. The present study is aimed to investigate the mechanisms of NMB-induced cyclo-oxygenase 2 (COX-2) expression and interleukin (IL)-6 generation in hu...

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Podrobná bibliografie
Vydáno v:Biosci Rep
Hlavní autoři: Zhu, Texuan, Chen, Jingfei, Zhao, Yanhua, Zhang, Jiejie, Peng, Qiaozhen, Huang, Jingrui, Luo, Jiefeng, Zhang, Weishe
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822491/
https://ncbi.nlm.nih.gov/pubmed/31527064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20192139
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