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pTuneos: prioritizing tumor neoantigens from next-generation sequencing data
BACKGROUND: Cancer neoantigens are expressed only in cancer cells and presented on the tumor cell surface in complex with major histocompatibility complex (MHC) class I proteins for recognition by cytotoxic T cells. Accurate and rapid identification of neoantigens play a pivotal role in cancer immun...
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| Veröffentlicht in: | Genome Med |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6822339/ https://ncbi.nlm.nih.gov/pubmed/31666118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0679-x |
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