α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles

OBJECTIVE: Although it is well established that a-calcitonin gene-related peptide (CGRP) stabilizes muscle-type cholinergic receptors nicotinic subunits (AChR), the underlying mechanism by which this neuropeptide regulates muscle protein metabolism and neuromuscular junction (NMJ) morphology is uncl...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Machado, Juliano, Silveira, Wilian A., Gonçalves, Dawit A., Schavinski, Aline Zanatta, Khan, Muzamil M., Zanon, Neusa M., Diaz, Mauricio Berriel, Rudolf, Rüdiger, Kettelhut, Isis C., Navegantes, Luiz C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822259/
https://ncbi.nlm.nih.gov/pubmed/31331823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.06.024
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