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Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells

Organoids derived from human pluripotent stem cells are interesting models to study mechanisms of morphogenesis and promising platforms for disease modeling and drug screening. However, they mostly remain incomplete as they lack stroma, tissue resident immune cells and in particular vasculature, whi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wörsdörfer, Philipp, Dalda, Nahide, Kern, Anna, Krüger, Sarah, Wagner, Nicole, Kwok, Chee Keong, Henke, Erik, Ergün, Süleyman
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821804/
https://ncbi.nlm.nih.gov/pubmed/31666641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52204-7
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