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Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients
Cigarette smoke is a risk factor for COPD and lung cancer. In cancer, epigenetic modifications affect the expression of Enhancer of Zester Homolog 2 (EZH2), and silenced disabled homolog 2 interacting protein gene (DAB2IP) (onco-suppressor gene) by Histone H3 tri-methylation in lysine 27 (H3K27me3)....
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821751/ https://ncbi.nlm.nih.gov/pubmed/31666665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52179-5 |
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