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Natural phenolic compounds potentiate hypoglycemia via inhibition of Dipeptidyl peptidase IV

Dipeptidyl peptidase IV (DPP IV) is a surface glycoprotein that can degrade glucagon like pepetide-1 (GLP-1) by decreasing blood sugar. Herbal medicines for diabetic therapy are widely used with acceptable efficacy but unsatisfied in advances. DPP IV was chosen as a template to employ molecular dock...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Po-Kai, Lin, Shian-Ren, Chang, Chia-Hsiang, Tsai, May-Jwan, Lee, Der-Nan, Weng, Ching-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821704/
https://ncbi.nlm.nih.gov/pubmed/31666589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52088-7
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