AST-120, an Oral Carbon Absorbent, Protects against the Progression of Atherosclerosis in a Mouse Chronic Renal Failure Model by Preserving sFlt-1 Expression Levels

Soluble Flt-1 (sFlt-1), an endogenous antagonist of the proatherogenic cytokine placental growth factor, is decreased in chronic kidney disease (CKD), leading to atherosclerotic progression. In this study, we investigated the effect of AST-120, an oral carbon adsorbent which can remove uremic toxins...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakada, Yasuki, Onoue, Kenji, Nakano, Tomoya, Ishihara, Satomi, Kumazawa, Takuya, Nakagawa, Hitoshi, Ueda, Tomoya, Nishida, Taku, Soeda, Tsunenari, Okayama, Satoshi, Watanabe, Makoto, Kawakami, Rika, Saito, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821698/
https://ncbi.nlm.nih.gov/pubmed/31666542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51292-9
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