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A predicted deleterious allele of the essential meiosis gene MND1, present in ~ 3% of East Asians, does not disrupt reproduction in mice

Infertility is a major health problem affecting ~15% of couples worldwide. Except for cases involving readily detectable chromosome aberrations, confident identification of a causative genetic defect is problematic. Despite the advent of genome sequencing for diagnostic purposes, the preponderance o...

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Библиографические подробности
Опубликовано в: :Mol Hum Reprod
Главные авторы: Tran, Tina N, Martinez, Julianna, Schimenti, John C
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821341/
https://ncbi.nlm.nih.gov/pubmed/31393579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaz048
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