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Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability
Chromosomally-encoded toxin-antitoxin complexes are ubiquitous in bacteria and regulate growth through the release of the toxin component typically in a stress-dependent manner. Type II ribosome-dependent toxins adopt a RelE-family RNase fold and inhibit translation by degrading mRNAs while bound to...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821326/ https://ncbi.nlm.nih.gov/pubmed/31501867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz760 |
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