METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis

Post-transcriptional RNA modifications, the epitranscriptome, play important roles in modulating the functions of RNA species. Modifications of rRNA are key for ribosome production and function. Identification and characterization of enzymes involved in epitranscriptome shaping is instrumental for t...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Haute, Lindsey Van, Hendrick, Alan G, D’Souza, Aaron R, Powell, Christopher A, Rebelo-Guiomar, Pedro, Harbour, Michael E, Ding, Shujing, Fearnley, Ian M, Andrews, Byron, Minczuk, Michal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821322/
https://ncbi.nlm.nih.gov/pubmed/31665743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz735
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