Diagnostic Accuracy of Early Secretory Antigenic Target-6–Free Interferon-gamma Release Assay Compared to QuantiFERON-TB Gold In-tube

BACKGROUND: Early secretory antigenic target-6 (ESAT-6) is an immunodominant Mycobacterium tuberculosis (M.tb) antigen included in novel vaccines against tuberculosis (TB) and in interferon-gamma (IFN-γ) release assays (IGRAs). Therefore, the availability of an ESAT-6–free IGRA is essential to deter...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Nemes, Elisa, Abrahams, Deborah, Scriba, Thomas J, Ratangee, Frances, Keyser, Alana, Makhethe, Lebohang, Erasmus, Mzwandile, Mabwe, Simbarashe, Bilek, Nicole, Rozot, Virginie, Geldenhuys, Hennie, Hatherill, Mark, Lempicki, Maria D, Holm, Line Lindebo, Bogardus, Leah, Ginsberg, Ann M, Blauenfeldt, Thomas, Smith, Bronwyn, Ellis, Ruth D, Loxton, Andre G, Walzl, Gerhard, Andersen, Peter, Ruhwald, Morten
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821223/
https://ncbi.nlm.nih.gov/pubmed/30668657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz034
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