Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

BACKGROUND: Genetics play an important role in intracranial aneurysm (IA) pathophysiology. Genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) that are linked to IA but how they affect disease pathobiology remains poorly understood. We used Encyclopedia of...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Poppenberg, Kerry E., Jiang, Kaiyu, Tso, Michael K., Snyder, Kenneth V., Siddiqui, Adnan H., Kolega, John, Jarvis, James N., Meng, Hui, Tutino, Vincent M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821037/
https://ncbi.nlm.nih.gov/pubmed/31666072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0591-7
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