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Estrogen-induced compensatory mechanisms protect IL-10-deficient mice from developing EAE
BACKGROUND: IL-10 knockout (KO) mice are protected from experimental autoimmune encephalomyelitis (EAE) with low-dose estrogen (E2) treatment similar to wild-type (WT) mice. Previous studies have demonstrated a decrease in tumor necrosis factor in all E2-treated groups, which led to the protection o...
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| Publicado no: | J Neuroinflammation |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821034/ https://ncbi.nlm.nih.gov/pubmed/31665042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1588-z |
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