Arabidopsis thaliana alternative dehydrogenases: a potential therapy for mitochondrial complex I deficiency? Perspectives and pitfalls

BACKGROUND: Complex I (CI or NADH:ubiquinone oxidoreductase) deficiency is the most frequent cause of mitochondrial respiratory chain defect. Successful attempts to rescue CI function by introducing an exogenous NADH dehydrogenase, such as the NDI1 from Saccharomyces cerevisiae (ScNDI1), have been r...

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Detaylı Bibliyografya
Yayımlandı:Orphanet J Rare Dis
Asıl Yazarlar: Catania, Alessia, Iuso, Arcangela, Bouchereau, Juliette, Kremer, Laura S., Paviolo, Marina, Terrile, Caterina, Bénit, Paule, Rasmusson, Allan G., Schwarzmayr, Thomas, Tiranti, Valeria, Rustin, Pierre, Rak, Malgorzata, Prokisch, Holger, Schiff, Manuel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821020/
https://ncbi.nlm.nih.gov/pubmed/31665043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-019-1185-3
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