DNA methylation in repeat negative prostate biopsies as a marker of missed prostate cancer

BACKGROUND: Men often undergo repeat prostate biopsies because of suspicion of missed cancer. We assessed if (i) methylation of selected genes in prostate tissue vary with aging and (ii) methylation alterations in repeat biopsies predict missed prostate cancer. METHODS: We conducted a case-control s...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Fiano, Valentina, Zugna, Daniela, Grasso, Chiara, Trevisan, Morena, Delsedime, Luisa, Molinaro, Luca, Cassoni, Paola, Papotti, Mauro, Merletti, Franco, Akre, Olof, Pettersson, Andreas, De Marco, Laura, Richiardi, Lorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820908/
https://ncbi.nlm.nih.gov/pubmed/31666119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0746-6
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