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A 96-multiplex capillary electrophoresis screening platform for product based evolution of P450 BM3

The main challenge that prevents a broader application of directed enzyme evolution is the lack of high-throughput screening systems with universal product analytics. Most directed evolution campaigns employ screening systems based on colorimetric or fluorogenic surrogate substrates or universal qua...

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Udgivet i:Sci Rep
Main Authors: Gärtner, Anna, Ruff, Anna Joëlle, Schwaneberg, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820799/
https://ncbi.nlm.nih.gov/pubmed/31664146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52077-w
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