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LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1

Cholesterol is a critical component of membranes and a precursor for hormones and other signaling molecules. Previously, we showed that unlike astrocytes, glioblastoma cells do not downregulate cholesterol synthesis when plated at high density. In this report, we show that high cell density induces...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Patel, Deven, Ahmad, Fahim, Kambach, Diane M., Sun, Qian, Halim, Alan S., Kramp, Tamalee, Camphausen, Kevin A., Stommel, Jayne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820787/
https://ncbi.nlm.nih.gov/pubmed/31664073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51865-8
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