Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model

Since ID93/GLA-SE was developed as a targeted BCG-prime booster vaccine, in the present study, we evaluated the protective efficacy of ID93/GLA-SE as a boost to a BCG-prime against the hypervirulent Mycobacterium tuberculosis (Mtb) K challenge to provide further information on the development and ap...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kwon, Kee Woong, Lee, Ara, Larsen, Sasha E., Baldwin, Susan L., Coler, Rhea N., Reed, Steven G., Cho, Sang-Nae, Ha, Sang-Jun, Shin, Sung Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820558/
https://ncbi.nlm.nih.gov/pubmed/31664157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52146-0
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