Early detection and staging of chronic liver diseases with a protein MRI contrast agent

Early diagnosis and noninvasive detection of liver fibrosis and its heterogeneity remain as major unmet medical needs for stopping further disease progression toward severe clinical consequences. Here we report a collagen type I targeting protein-based contrast agent (ProCA32.collagen1) with strong...

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Vydáno v:Nat Commun
Hlavní autoři: Salarian, Mani, Turaga, Ravi Chakra, Xue, Shenghui, Nezafati, Maysam, Hekmatyar, Khan, Qiao, Jingjuan, Zhang, Yinwei, Tan, Shanshan, Ibhagui, Oluwatosin Y., Hai, Yan, Li, Jibiao, Mukkavilli, Rao, Sharma, Malvika, Mittal, Pardeep, Min, Xiaoyi, Keilholz, Shella, Yu, Liqing, Qin, Gengshen, Farris, Alton Brad, Liu, Zhi-Ren, Yang, Jenny J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820552/
https://ncbi.nlm.nih.gov/pubmed/31664017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11984-2
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