Silencing of Neuropilins and GIPC1 in pancreatic ductal adenocarcinoma exerts multiple cellular and molecular antitumor effects

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer mortality, with new treatment options urgently needed. Neuropilins-1/-2 (NRP1, NRP2) are receptors for semaphorins and angiogenic growth factors, while the GAIP interacting protein C-terminus 1 (GIPC1, aka Synectin) interacts with...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Borchardt, Hannes, Schulz, Alexander, Datta, Kaustubh, Muders, Michael H., Aigner, Achim
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820541/
https://ncbi.nlm.nih.gov/pubmed/31664117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51881-8
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