Methylation-mediated silencing of miR-133a-3p promotes breast cancer cell migration and stemness via miR-133a-3p/MAML1/DNMT3A positive feedback loop

BACKGROUND: miR-133a-3p has been recently discovered to be down-regulated in various human malignancies, including breast cancer, and reduced miR-133a-3p levels have been significantly associated with breast cancer cell growth and invasion. However, the regulatory mechanisms leading to abnormal expr...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Shi, Wanyue, Tang, Tingting, Li, Xinping, Deng, Siwei, Li, Ruiyi, Wang, Yingshan, Wang, Yifei, Xia, Tiansong, Zhang, Yanfeng, Zen, Ke, Jin, Liang, Pan, Yi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819615/
https://ncbi.nlm.nih.gov/pubmed/31660998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1400-z
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