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APOE Modifies the Interaction of Entorhinal Cerebral Blood Flow and Cortical Thickness on Memory Function in Cognitively Normal Older Adults

OBJECTIVE: The ε4 allele of the apolipoprotein E (APOE) gene increases risk for cognitive decline in normal and pathologic aging. However, precisely how APOE ε4 exerts its negative impact on cognition is poorly understood. The present study aimed to determine whether APOE genotype (ε4+ vs. ε4-) modi...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Hays, Chelsea C., Zlatar, Zvinka Z., Meloy, M.J., Bondi, Mark W., Gilbert, Paul E., Liu, Thomas, Helm, Jonathan L., Wierenga, Christina E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819270/
https://ncbi.nlm.nih.gov/pubmed/31493534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2019.116162
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