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Calcium channel Orai1 promotes lymphocyte IL-17 expression and progressive kidney injury
We hypothesized that the store-operated calcium entry (SOCE) channel, Orai1, participates in the activation of Th17 cells and influences renal injury. In rats, following renal ischemia/reperfusion (I/R), there was a rapid and sustained influx of Orai1(+) CD4 T cells and IL-17 expression was restrict...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6819116/ https://ncbi.nlm.nih.gov/pubmed/31415242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126108 |
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