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Mutation rate variability as a driving force in adaptive evolution

Mutation rate is a key determinant of the pace as well as outcome of evolution, and variability in this rate has been shown in different scenarios to play a key role in evolutionary adaptation and resistance evolution under stress caused by selective pressure. Here we investigate the dynamics of res...

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Detalhes bibliográficos
Publicado no:Phys Rev E
Main Authors: Engelhardt, Dalit, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819004/
https://ncbi.nlm.nih.gov/pubmed/30934244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.99.022424
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