Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis

The male-specific region of the Y chromosome (MSY) remains one of the most unexplored regions of the genome. We sought to examine how the genetic variants of the MSY influence male susceptibility to coronary artery disease (CAD) and atherosclerosis. APPROACH AND RESULTS: Analysis of 129 133 men from...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Eales, James M., Maan, Akhlaq A., Xu, Xiaoguang, Michoel, Tom, Hallast, Pille, Batini, Chiara, Zadik, Daniel, Prestes, Priscilla R., Molina, Elsa, Denniff, Matthew, Schroeder, Juliane, Bjorkegren, Johan L.M., Thompson, John, Maffia, Pasquale, Guzik, Tomasz J., Keavney, Bernard, Jobling, Mark A., Samani, Nilesh J., Charchar, Fadi J., Tomaszewski, Maciej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2019
Soggetti:
Clinical and Population Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818981/
https://ncbi.nlm.nih.gov/pubmed/31644355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312405
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