CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro

BACKGROUND AND AIM: The hepatitis C virus (HCV) is a single-strand RNA virus that infects millions of people worldwide. Recent advances in therapy have led to viral cure using two- and three- drug combinations of direct acting inhibitors of viral replication. CCR5 is a chemokine receptor that is exp...

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Bibliographic Details
Published in:PLoS One
Main Authors: Blackard, Jason T., Kong, Ling, Rouster, Susan D., Karns, Rebekah, Horn, Paul S., Kottilil, Shyam, Shata, M. Tarek, Sherman, Kenneth E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818973/
https://ncbi.nlm.nih.gov/pubmed/31661521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224523
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