Glycolytic and Mitochondrial Metabolism Are Essential for Muscle Progenitor Cell Proliferation and Impacted by Pyruvate Kinase M2 (P08-135-19)

OBJECTIVES: The metabolic requirements for muscle progenitor cell (MPC), the cell required for skeletal muscle regeneration, are ambiguous. We identified that pyruvate kinase M2 (PKM2), a glycolytic enzyme (canonical) and metabolic regulator (non-canonical) promotes MPC proliferation. Our objective...

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Bibliografiske detaljer
Udgivet i:Curr Dev Nutr
Main Authors: Blum, Jamie, Gheller, Brandon, Yi, Jennie, Thalacker-Mercer, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Energy and Macronutrient Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818828/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz044.P08-135-19
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