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Serine hydroxymethyltransferase 1 promoter hypermethylation increases the risk of essential hypertension

BACKGROUND: Serine hydroxymethyltransferase 1 (SHMT1) is an enzyme involved in folic acid metabolism and is known to contribute to the development of hypertension. We evaluated the relationship between SHMT1 promoter methylation and essential hypertension (EH). METHODS: Quantitative methylation‐spec...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Xu, Guodong, Wang, Changyi, Ying, Xiuru, Kong, Fanqian, Ji, Huihui, Zhao, Jinshun, Zhang, Xiaohong, Duan, Shiwei, Han, Liyuan, Li, Li
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818578/
https://ncbi.nlm.nih.gov/pubmed/30411815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22712
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