Tumour‐derived transforming growth factor‐β signalling contributes to fibrosis in patients with cancer cachexia

BACKGROUND: Cachexia is a paraneoplastic syndrome related with poor prognosis. The tumour micro‐environment contributes to systemic inflammation and increased oxidative stress as well as to fibrosis. The aim of the present study was to characterise the inflammatory circulating factors and tumour mic...

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Publicat a:J Cachexia Sarcopenia Muscle
Autors principals: Lima, Joanna D.C.C., Simoes, Estefania, de Castro, Gabriela, Morais, Mychel Raony P.T., de Matos‐Neto, Emidio M., Alves, Michele J., Pinto, Nelson I., Figueredo, Raquel G., Zorn, Telma M.T., Felipe‐Silva, Aloísio S., Tokeshi, Flavio, Otoch, José P., Alcantara, Paulo, Cabral, Fernanda J., Ferro, Emer S., Laviano, Alessandro, Seelaender, Marilia
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818454/
https://ncbi.nlm.nih.gov/pubmed/31273954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12441
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