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Tumour‐derived transforming growth factor‐β signalling contributes to fibrosis in patients with cancer cachexia

BACKGROUND: Cachexia is a paraneoplastic syndrome related with poor prognosis. The tumour micro‐environment contributes to systemic inflammation and increased oxidative stress as well as to fibrosis. The aim of the present study was to characterise the inflammatory circulating factors and tumour mic...

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Bibliographic Details
Published in:J Cachexia Sarcopenia Muscle
Main Authors: Lima, Joanna D.C.C., Simoes, Estefania, de Castro, Gabriela, Morais, Mychel Raony P.T., de Matos‐Neto, Emidio M., Alves, Michele J., Pinto, Nelson I., Figueredo, Raquel G., Zorn, Telma M.T., Felipe‐Silva, Aloísio S., Tokeshi, Flavio, Otoch, José P., Alcantara, Paulo, Cabral, Fernanda J., Ferro, Emer S., Laviano, Alessandro, Seelaender, Marilia
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818454/
https://ncbi.nlm.nih.gov/pubmed/31273954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12441
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