MicroRNA-425-5p Expression Affects BRAF/RAS/MAPK Pathways In Colorectal Cancers

Colorectal cancer (CRC) is a leading cause of cancer death worldwide and about 20% is metastatic at diagnosis and untreatable. The anti-EGFR therapy in metastatic patients is led by the presence of KRAS-mutations in tumor tissue. KRAS-wild-type CRC patients showed a positive response rate of about 7...

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Bibliographic Details
Published in:Int J Med Sci
Main Authors: Angius, Andrea, Pira, Giovanna, Scanu, Antonio Mario, Uva, Paolo, Sotgiu, Giovanni, Saderi, Laura, Manca, Alessandra, Serra, Caterina, Uleri, Elena, Piu, Claudia, Caocci, Maurizio, Ibba, Gabriele, Zinellu, Angelo, Cesaraccio, Maria Rosaria, Sanges, Francesca, Muroni, Maria Rosaria, Dolei, Antonina, Cossu-Rocca, Paolo, De Miglio, Maria Rosaria
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818206/
https://ncbi.nlm.nih.gov/pubmed/31673240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.35269
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