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Is there a link between genetic defects in the complement cascade and Porphyromonas gingivalis in Alzheimer’s disease?

Defects, as determined by Genome-Wide Association Studies (GWAS), in the complement cascade of innate immunity have been suggested to play a key role in Alzheimer’s disease (AD). These defective genes encode sub-component 1s (C1s), complement receptor 1, complement component 9, and clusterin, a flui...

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Bibliografske podrobnosti
izdano v:J Oral Microbiol
Main Authors: Olsen, Ingar, Singhrao, Sim K
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818111/
https://ncbi.nlm.nih.gov/pubmed/31893014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20002297.2019.1676486
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