Oral levosimendan in amyotrophic lateral sclerosis: a phase II multicentre, randomised, double-blind, placebo-controlled trial

OBJECTIVE: To evaluate the efficacy and safety of oral levosimendan in patients with amyotrophic lateral sclerosis (ALS). This phase II, randomised, double-blind, placebo-controlled, crossover, three-period study with 6 months open-label follow-up enrolled adults with ALS and sitting slow vital capa...

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Detalles Bibliográficos
Publicado en:J Neurol Neurosurg Psychiatry
Autores principales: Al-Chalabi, Ammar, Shaw, Pamela, Leigh, P Nigel, van den Berg, Leonard, Hardiman, Orla, Ludolph, Albert, Aho, Valtteri V, Sarapohja, Toni, Kuoppamäki, Mikko
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2019
Materias:
Neuromuscular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817985/
https://ncbi.nlm.nih.gov/pubmed/31315908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2018-320288
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