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Ribosomal protein uL3 targets E2F1 and Cyclin D1 in cancer cell response to nucleolar stress

Several experimental strategies in the treatment of cancer include drug alteration of cell cycle regulatory pathways as a useful strategy. Extra-ribosomal functions of human ribosomal protein L3 (uL3) may affect DNA repair, cell cycle arrest and apoptosis. In the present study, we demonstrated that...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Pecoraro, Annalisa, Carotenuto, Pietro, Russo, Giulia, Russo, Annapina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817900/
https://ncbi.nlm.nih.gov/pubmed/31659203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51723-7
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