Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Insulin deficiency in type 1 diabetes (T1D) is generally considered a consequence of immune‐mediated specific beta‐cell loss. Since healthy pancreatic islets consist of ~65% beta cells, this would lead to reduced islet size, while the number of islets per pancreas volume (islet density) would not be...

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Bibliografiske detaljer
Udgivet i:J Pathol Clin Res
Main Authors: Seiron, Peter, Wiberg, Anna, Kuric, Enida, Krogvold, Lars, Jahnsen, Frode L, Dahl‐Jørgensen, Knut, Skog, Oskar, Korsgren, Olle
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817830/
https://ncbi.nlm.nih.gov/pubmed/31493350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.140
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