Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway

Glioblastomas (GBM) are brain tumors with a poor prognosis despite treatment that combines surgical resection and radio-chemotherapy. These tumors are characterized by abundant vascularization and significant cellular heterogeneity including GBM stem-like cells (GSC) which contribute to tumor aggres...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Deshors, Pauline, Toulas, Christine, Arnauduc, Florent, Malric, Laure, Siegfried, Aurore, Nicaise, Yvan, Lemarié, Anthony, Larrieu, Dorian, Tosolini, Marie, Cohen-Jonathan Moyal, Elizabeth, Courtade-Saidi, Monique, Evrard, Solène M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817826/
https://ncbi.nlm.nih.gov/pubmed/31659157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2055-6
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